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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K15
All Species:
16.36
Human Site:
Y65
Identified Species:
45
UniProt:
Q6ZN16
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZN16
NP_001001671.2
1313
147437
Y65
R
R
A
L
R
A
V
Y
V
R
S
E
S
S
Q
Chimpanzee
Pan troglodytes
XP_001171211
1375
154924
Y96
S
R
R
T
T
V
A
Y
V
I
N
E
A
S
Q
Rhesus Macaque
Macaca mulatta
XP_001111127
1297
143635
P69
G
E
G
T
E
A
E
P
L
P
L
R
C
L
R
Dog
Lupus familis
XP_548885
1422
158482
Y161
R
R
A
L
R
A
V
Y
V
R
S
E
S
P
P
Cat
Felis silvestris
Mouse
Mus musculus
A2AQW0
1331
149309
Y68
R
R
A
L
R
A
V
Y
V
R
S
E
S
S
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514080
1407
157705
Y155
G
R
G
L
R
A
V
Y
V
L
N
E
G
A
G
Chicken
Gallus gallus
XP_419725
1260
143069
F52
A
F
R
Q
P
S
L
F
Y
H
L
G
V
R
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001155222
1364
153160
Y83
S
R
A
V
T
V
A
Y
V
R
N
S
E
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202919
1288
145042
L57
D
F
G
E
T
K
V
L
D
R
F
Y
A
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58
44.2
81.6
N.A.
86
N.A.
N.A.
70.8
57.3
N.A.
54.4
N.A.
N.A.
N.A.
N.A.
45.4
Protein Similarity:
100
72.6
60.9
86.4
N.A.
90.3
N.A.
N.A.
79.4
73.5
N.A.
71.5
N.A.
N.A.
N.A.
N.A.
62.2
P-Site Identity:
100
40
6.6
86.6
N.A.
100
N.A.
N.A.
53.3
0
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
53.3
20
86.6
N.A.
100
N.A.
N.A.
66.6
26.6
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
45
0
0
56
23
0
0
0
0
0
23
23
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% C
% Asp:
12
0
0
0
0
0
0
0
12
0
0
0
0
0
12
% D
% Glu:
0
12
0
12
12
0
12
0
0
0
0
56
12
0
12
% E
% Phe:
0
23
0
0
0
0
0
12
0
0
12
0
0
0
0
% F
% Gly:
23
0
34
0
0
0
0
0
0
0
0
12
12
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
45
0
0
12
12
12
12
23
0
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
34
0
0
0
0
% N
% Pro:
0
0
0
0
12
0
0
12
0
12
0
0
0
12
12
% P
% Gln:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
34
% Q
% Arg:
34
67
23
0
45
0
0
0
0
56
0
12
0
12
12
% R
% Ser:
23
0
0
0
0
12
0
0
0
0
34
12
34
34
12
% S
% Thr:
0
0
0
23
34
0
0
0
0
0
0
0
0
12
0
% T
% Val:
0
0
0
12
0
23
56
0
67
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
12
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _